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Low testosterone levels

MRAS · rs7626388

What the study found

Who was studied 13,409 European ancestry male cases, 98,267 European ancestry male controls; replicated in 4,426 European ancestry male cases, 32,800 European ancestry male controls.

The effect The reported allele is G; the catalogue records no effect size ; p = 2 × 10−10.

How common The G allele had a frequency of about 34% in the people studied.

Where it sits Chromosome 3, band 3q22.3 — in an intron of MRAS.

What each result means

A/A No copy of the version the research linked to Low testosterone levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Low testosterone levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Low testosterone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7626388

What is rs7626388?

rs7626388 is a single position in the genome, in or near the MRAS gene. Published research associates it with low testosterone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7626388 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7626388 come from?

GWAS Catalog, European urology open science 2021, PMID:34337532. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Low testosterone levels (rs7626388). MyGeneLog™. https://www.mygenelog.com/variants/rs7626388

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