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COVID-19 (hospitalized covid vs population)

XCR1 · rs7623460

What the study found

Who was studied 4,702 Admixed Latin American ancestry cases, 68,573 Admixed Latin American ancestry controls, European, African, East Asian, South Asian or Admixed American individuals (See The COVID-19 Host Genetics Initiative, v7 ALL B2).

The effect Each copy of the A allele shifted the measure 0.117 lower (95% confidence interval 0.1-0.134); p = 2 × 10−41.

Where it sits Chromosome 3, band 3p21.31 — in an intron of XCR1.

What each result means

A/A Two copies of the version the research linked to COVID-19 (hospitalized covid vs population). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to COVID-19 (hospitalized covid vs population). That is a smaller link than two copies.
C/C No copy of the version the research linked to COVID-19 (hospitalized covid vs population). This is the starting point the study compared everyone against.
Source

Questions about rs7623460

What is rs7623460?

rs7623460 is a single position in the genome, in or near the XCR1 gene. Published research associates it with covid-19 (hospitalized covid vs population). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7623460 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7623460 come from?

GWAS Catalog, eLife 2024, PMID:39361370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

COVID-19 (hospitalized covid vs population) (rs7623460). MyGeneLog™. https://www.mygenelog.com/variants/rs7623460

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