Standard

Waist-hip ratio

RETREG3 · rs76189032

Where this position leads

Condition: Waist-to-Hip Ratio (Body Fat Distribution)

rs76189032 Condition: Waist-to-Hip Ratio (Body Fat Distribution) Waist-to-Hip Ratio (Body Fat Distri… Condition rs76189032 rs76189032 RETREG3

What the study found

Who was studied 381,152 European female individuals.

The effect Each copy of the T allele shifted the measure 0.0285 higher (95% confidence interval 0.021-0.036); p = 1 × 10−14.

How common The T allele had a frequency of about 8% in the people studied.

Where it sits Chromosome 17, band 17q21.2 — in an intron of RETREG3.

What each result means

C/C No copy of the version the research linked to Waist-hip ratio. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Waist-hip ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Waist-hip ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs76189032

What is rs76189032?

rs76189032 is a single position in the genome, in or near the RETREG3 gene. Published research associates it with waist-hip ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs76189032 linked to?

On MyGeneLog this position is linked to Waist-to-Hip Ratio (Body Fat Distribution). The research behind each link, and its sources, are set out on that condition page.

Does having rs76189032 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs76189032 come from?

GWAS Catalog, Human molecular genetics 2019, PMID:30239722. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Waist-hip ratio (rs76189032). MyGeneLog™. https://www.mygenelog.com/variants/rs76189032

← See all variants