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Who was studied 11,024 psoriasis cases, 60,801 coronary artery disease cases, 139,840 controls.
The effect
The reported allele is C; the catalogue records no effect size
; p = 3 × 10−19.
How common The C allele had a frequency of about 94% in the people studied.
Where it sits Chromosome 12, band 12q13.3 — between genes, 1.3 kb from COQ10A.
What each result means
C/CTwo copies of the version the research linked to Psoriasis or coronary artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Psoriasis or coronary artery disease. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Psoriasis or coronary artery disease. This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 36323703 · open access
Questions about rs76151170
What is rs76151170?
rs76151170 is a single position in the genome, in or near the near COQ10A gene. Published research associates it with psoriasis or coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs76151170 linked to?
On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs76151170 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs76151170 come from?
GWAS Catalog, Nature communications 2022, PMID:36323703. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 12426Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot4Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others6Total12Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Psoriasis or coronary artery disease (rs76151170). MyGeneLog™. https://www.mygenelog.com/variants/rs76151170