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Neuroticism

EPHB1 · rs7613213

Where this position leads

Condition: Neuroticism

rs7613213 Condition: Neuroticism Neuroticism Condition rs7613213 rs7613213 EPHB1

What the study found

Who was studied 523,783 European ancestry individuals; replicated in 59,206 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0098 lower (95% confidence interval 0.0063-0.0133); p = 4 × 10−8.

How common The T allele had a frequency of about 36% in the people studied.

Where it sits Chromosome 3, band 3q22.2 — in an intron of EPHB1.

What each result means

C/C No copy of the version the research linked to Neuroticism. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Neuroticism. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Neuroticism. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7613213

What is rs7613213?

rs7613213 is a single position in the genome, in or near the EPHB1 gene. Published research associates it with neuroticism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7613213 linked to?

On MyGeneLog this position is linked to Neuroticism. The research behind each link, and its sources, are set out on that condition page.

Does having rs7613213 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7613213 come from?

GWAS Catalog, Nat Genet 2019, PMID:30643256. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Neuroticism (rs7613213). MyGeneLog™. https://www.mygenelog.com/variants/rs7613213

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