Sensitive

Response to paliperidone in schizophrenia (positive Marder score)

near KCNIP1 · rs76131026

Where this position leads

Condition: Schizophrenia

rs76131026 Condition: Schizophrenia Schizophrenia Condition rs76131026 rs76131026 near KCNIP1

What the study found

Who was studied 1,390 European ancestry cases.

The effect Each copy of the G allele shifted the measure 10.7 lower; p = 1 × 10−8.

Where it sits Chromosome 5, band 5q35.1 — between genes, 1.2 kb from KCNIP1.

What each result means

A/A No copy of the version the research linked to Response to paliperidone in schizophrenia (positive Marder score). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Response to paliperidone in schizophrenia (positive Marder score). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Response to paliperidone in schizophrenia (positive Marder score). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs76131026

What is rs76131026?

rs76131026 is a single position in the genome, in or near the near KCNIP1 gene. Published research associates it with response to paliperidone in schizophrenia (positive marder score). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs76131026 linked to?

On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.

Does having rs76131026 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs76131026 come from?

GWAS Catalog, Pharmacogenetics and genomics 2017, PMID:27846195. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Response to paliperidone in schizophrenia (positive Marder score) (rs76131026). MyGeneLog™. https://www.mygenelog.com/variants/rs76131026

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