Standard

Appendicular lean mass

PPARG · rs7610055

What the study found

Who was studied 450,243 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0373 lower (95% confidence interval 0.032-0.043); p = 4 × 10−38.

How common The A allele had a frequency of about 12% in the people studied.

Where it sits Chromosome 3, band 3p25.2 — in an intron of PPARG.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Appendicular lean mass compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Appendicular lean mass.
G/G Published research associates this genotype with typical/baseline likelihood of Appendicular lean mass — no copies of the reported risk allele.
Source

Questions about rs7610055

What is rs7610055?

rs7610055 is a single position in the genome, in or near the PPARG gene. Published research associates it with appendicular lean mass. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7610055 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7610055 come from?

GWAS Catalog, Communications biology 2020, PMID:33097823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Appendicular lean mass (rs7610055). MyGeneLog™. https://www.mygenelog.com/variants/rs7610055

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