Standard

Diastolic blood pressure

near LINC01819 · rs76099932

Where this position leads

Condition: Blood Pressure

rs76099932 Condition: Blood Pressure Blood Pressure Condition rs76099932 rs76099932 near LINC018…

What the study found

Who was studied 349,328 British ancestry individuals; replicated in 144,022 European ancestry,African ancestry,Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.03 higher (95% confidence interval 0.022-0.038); p = 3 × 10−15.

Where it sits Chromosome 2, band 2p21 — between genes, 32.7 kb from LINC01819.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Diastolic blood pressure — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Diastolic blood pressure.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Diastolic blood pressure compared to the general population.
Source

Questions about rs76099932

What is rs76099932?

rs76099932 is a single position in the genome, in or near the near LINC01819 gene. Published research associates it with diastolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs76099932 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs76099932 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs76099932 come from?

GWAS Catalog, Nature medicine 2024, PMID:38459180. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Diastolic blood pressure (rs76099932). MyGeneLog™. https://www.mygenelog.com/variants/rs76099932

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