G/GPublished research associates this genotype with typical/baseline likelihood of Alzheimer disease and age of onset — no copies of the reported risk allele.
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Alzheimer disease and age of onset.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Alzheimer disease and age of onset compared to the general population.
Molecular psychiatry · 2016 · PMID 26830138 · open access
Questions about rs7609954
What is rs7609954?
rs7609954 is a single position in the genome, in or near the PTPRG gene. Published research associates it with alzheimer disease and age of onset. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7609954 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs7609954 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7609954 come from?
GWAS Catalog, Mol Psychiatry 2016, PMID:26830138. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.