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Body mass index

DIS3L · rs76095247

Where this position leads

Conditions: Childhood Body Mass Index, Obesity and Body Weight

rs76095247 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition Condition: Obesity and Body Weight Obesity and Body Weight Condition rs76095247 rs76095247 DIS3L

What the study found

Who was studied 441,761 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0141 higher (95% confidence interval 0.0097-0.0186); p = 2 × 10−9.

Where it sits Chromosome 15, band 15q22.31 — in an intron of DIS3L.

What each result means

A/A Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
C/C No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Source

Questions about rs76095247

What is rs76095247?

rs76095247 is a single position in the genome, in or near the DIS3L gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs76095247 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index, Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs76095247 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs76095247 come from?

GWAS Catalog, Diabetologia 2023, PMID:37280435. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs76095247). MyGeneLog™. https://www.mygenelog.com/variants/rs76095247

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