Standard

Serum phosphate levels

MAFTRR · rs76075303

Where this position leads

Condition: Gout

rs76075303 Condition: Gout Gout Condition rs76075303 rs76075303 MAFTRR

What the study found

Who was studied 312,888 European ancestry individuals, 5,568 African ancestry individuals, 6,685 South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0341 lower (95% confidence interval 0.023-0.045); p = 3 × 10−9.

Where it sits Chromosome 16, band 16q23.2 — in an intron of MAFTRR.

What each result means

C/C Two copies of the version the research linked to Serum phosphate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Serum phosphate levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Serum phosphate levels. This is the starting point the study compared everyone against.
Source

Questions about rs76075303

What is rs76075303?

rs76075303 is a single position in the genome, in or near the MAFTRR gene. Published research associates it with serum phosphate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs76075303 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs76075303 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs76075303 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Serum phosphate levels (rs76075303). MyGeneLog™. https://www.mygenelog.com/variants/rs76075303

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