Standard

Hernia

near ELN · rs76027228

Where this position leads

Condition: Inguinal Hernia

rs76027228 Condition: Inguinal Hernia Inguinal Hernia Condition rs76027228 rs76027228 near ELN

What the study found

Who was studied 57,418 European ancestry cases, 287,090 European ancestry controls.

The effect The reported allele is C; the catalogue records no effect size ; p = 5 × 10−10.

Where it sits Chromosome 7, band 7q11.23 — between genes, 19.5 kb from ELN.

What each result means

C/C Two copies of the version the research linked to Hernia. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Hernia. That is a smaller link than two copies.
T/T No copy of the version the research linked to Hernia. This is the starting point the study compared everyone against.
Source

Questions about rs76027228

What is rs76027228?

rs76027228 is a single position in the genome, in or near the near ELN gene. Published research associates it with hernia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs76027228 linked to?

On MyGeneLog this position is linked to Inguinal Hernia. The research behind each link, and its sources, are set out on that condition page.

Does having rs76027228 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs76027228 come from?

GWAS Catalog, PloS one 2022, PMID:36584111. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hernia (rs76027228). MyGeneLog™. https://www.mygenelog.com/variants/rs76027228

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