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Sum neutrophil eosinophil counts

MAML1 · rs76025697

Where this position leads

Condition: Blood Cell Counts

rs76025697 Condition: Blood Cell Counts Blood Cell Counts Condition rs76025697 rs76025697 MAML1

What the study found

Who was studied 170,384 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0251 lower (95% confidence interval 0.018-0.032); p = 4 × 10−12.

How common The A allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 5, band 5q35.3 — in an intron of MAML1.

What each result means

A/A Two copies of the version the research linked to Sum neutrophil eosinophil counts. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Sum neutrophil eosinophil counts. That is a smaller link than two copies.
G/G No copy of the version the research linked to Sum neutrophil eosinophil counts. This is the starting point the study compared everyone against.
Source

Questions about rs76025697

What is rs76025697?

rs76025697 is a single position in the genome, in or near the MAML1 gene. Published research associates it with sum neutrophil eosinophil counts. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs76025697 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs76025697 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs76025697 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sum neutrophil eosinophil counts (rs76025697). MyGeneLog™. https://www.mygenelog.com/variants/rs76025697

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