Sensitive

Estimated glomerular filtration rate in sickle cell disease

near MARK2P15 · rs76023706

What the study found

Who was studied 966 individuals.

The effect Each copy of the G allele shifted the measure 19.8 lower (95% confidence interval 12.9-26.64); p = 2 × 10−8.

Where it sits Chromosome 10, band 10q23.1 — between genes, 74.2 kb from MARK2P15.

What each result means

G/G Two copies of the version the research linked to Estimated glomerular filtration rate in sickle cell disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Estimated glomerular filtration rate in sickle cell disease. That is a smaller link than two copies.
T/T No copy of the version the research linked to Estimated glomerular filtration rate in sickle cell disease. This is the starting point the study compared everyone against.
Source

Questions about rs76023706

What is rs76023706?

rs76023706 is a single position in the genome, in or near the near MARK2P15 gene. Published research associates it with estimated glomerular filtration rate in sickle cell disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs76023706 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs76023706 come from?

GWAS Catalog, Blood advances 2026, PMID:42616615. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Estimated glomerular filtration rate in sickle cell disease (rs76023706). MyGeneLog™. https://www.mygenelog.com/variants/rs76023706

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