Standard

Killer cell immunoglobulin-like receptor 2DL2 levels

NELFE · rs760070

What the study found

Who was studied 10,708 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.209 lower (95% confidence interval 0.16-0.25); p = 3 × 10−20.

How common The T allele had a frequency of about 90% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — in the 3′ untranslated region of NELFE.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Killer cell immunoglobulin-like receptor 2DL2 levels — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Killer cell immunoglobulin-like receptor 2DL2 levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Killer cell immunoglobulin-like receptor 2DL2 levels compared to the general population.
Source

Questions about rs760070

What is rs760070?

rs760070 is a single position in the genome, in or near the NELFE gene. Published research associates it with killer cell immunoglobulin-like receptor 2dl2 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs760070 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs760070 come from?

GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Killer cell immunoglobulin-like receptor 2DL2 levels (rs760070). MyGeneLog™. https://www.mygenelog.com/variants/rs760070

← See all variants