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Standard
Monocyte count
near SESN3 · rs75963851
1 2721723111Reads by AI crawlersClaude0ChatGPT0Google · Gemini2Perplexity1Meta AI0Microsoft · Copilot7Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others11Total27Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
Strength of the evidence
2 / 4
Its strongest genetic-study result is p = 10−45, with 10 associations in the GWAS Catalog.
How this is scored
4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.
What the study found
Who was studied 88,929 East Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0757 SD units higher (95% confidence interval 0.058-0.094); p = 3 × 10−16.
How common The A allele had a frequency of about 93% in the people studied.
Where it sits Chromosome 11, band 11q21 — between genes, 53.3 kb from LNCRNA-IUR.
How common each version is
AG
KoreanKRGDB
A 94.5% · G 5.5%
KoreanKorea4K
A 95.2% · G 4.8%
KoreanKorea1K
A 95.5% · G 4.5%
Japanese ToMMo
A 92.4% · G 7.6%
Vietnamese
A 93.1% · G 6.9%
World gnomAD
A 99.6% · G 0.4%
World 1000 Genomes
A 98.5% · G 1.5%
World TOPMed
A 99.6% · G 0.4%
By ancestry gnomAD
East Asian
A 95.2% · G 4.8%
European (non-Finnish)
A 99.9%
African / African American
A 99.6%
South Asian
A 98.6% · G 1.4%
Admixed American (Latino)
A 99.8%
Ashkenazi Jewish
A 99.3% · G 0.7%
The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study. The ancestry rows are gnomAD's own groups (via Ensembl), as the survey defines them, not races.
What each result means
A/ATwo copies of the version the research linked to Monocyte count. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Monocyte count. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Monocyte count. This is the starting point the study compared everyone against.
1 2721723111Reads by AI crawlersClaude0ChatGPT0Google · Gemini2Perplexity1Meta AI0Microsoft · Copilot7Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others11Total27Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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