Standard
Branched-chain amino acid levels (Isoleucine)
DDX19A · rs75950518
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Branched-chain amino acid levels (Isoleucine) compared to the general population.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Branched-chain amino acid levels (Isoleucine).
T/T
Published research associates this genotype with typical/baseline likelihood of Branched-chain amino acid levels (Isoleucine) — no copies of the reported risk allele.
Source
Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis
Lotta LA,
Scott RA,
Sharp SJ,
Burgess S,
Luan J,
Tillin T,
Schmidt AF,
Imamura F,
Stewart ID,
Perry JR,
Marney L,
Koulman A
and 16 more — show all
Karoly ED,
Forouhi NG,
Sjögren RJ,
Näslund E,
Zierath JR,
Krook A,
Savage DB,
Griffin JL,
Chaturvedi N,
Hingorani AD,
Khaw KT,
Barroso I,
McCarthy MI,
O'Rahilly S,
Wareham NJ,
Langenberg C
PLoS medicine · 2016 · PMID 27898682 · open access
Questions about rs75950518
What is rs75950518?
rs75950518 is a single position in the genome, in or near the DDX19A gene. Published research associates it with branched-chain amino acid levels (isoleucine). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs75950518 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs75950518 come from?
GWAS Catalog, PLoS Med 2016, PMID:27898682. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants