A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Total bilirubin levels compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Total bilirubin levels.
G/GPublished research associates this genotype with typical/baseline likelihood of Total bilirubin levels — no copies of the reported risk allele.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs75944157
What is rs75944157?
rs75944157 is a single position in the genome, in or near the SPTB gene. Published research associates it with total bilirubin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs75944157 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs75944157 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs75944157 come from?
GWAS Catalog, Nat Genet 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.