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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 283,227 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0114 higher (95% confidence interval 0.0092-0.0136); p = 8 × 10−25.
Where it sits Chromosome 10, band 10q25.2 — in an intron of TCF7L2.
What each result means
A/ATwo copies of the version the research linked to Diabetes (standard GWA). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Diabetes (standard GWA). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Diabetes (standard GWA). This is the starting point the study compared everyone against.
Nature human behaviour · 2023 · PMID 37106081 · open access
Questions about rs75933965
What is rs75933965?
rs75933965 is a single position in the genome, in or near the TCF7L2 gene. Published research associates it with diabetes (standard gwa). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs75933965 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs75933965 come from?
GWAS Catalog, Nature human behaviour 2023, PMID:37106081. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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