Aspartate aminotransferase to alanine aminotransferase ratio
SLC39A4 · rs75920625
0 711212Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple1China (ByteDance, Huawei, Baidu…)0Others2Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 341,165 European ancestry individuals, 5,981 African ancestry individuals, 7,309 South Asian ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.117 higher (95% confidence interval 0.083-0.152); p = 3 × 10−11.
Where it sits Chromosome 8, band 8q24.3 — a missense change in SLC39A4.
What ClinVar records
ClassificationBenign/Likely benign for Hereditary acrodermatitis enteropathica; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 4 submitters), last evaluated 2026-02-02.
ClinVar record 362239NM_130849.4(SLC39A4):c.1141A>G (p.Thr381Ala)
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
C/CTwo copies of the version the research linked to Aspartate aminotransferase to alanine aminotransferase ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Aspartate aminotransferase to alanine aminotransferase ratio. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Aspartate aminotransferase to alanine aminotransferase ratio. This is the starting point the study compared everyone against.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs75920625
What is rs75920625?
rs75920625 is a single position in the genome, in or near the SLC39A4 gene. Published research associates it with aspartate aminotransferase to alanine aminotransferase ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs75920625 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs75920625 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs75920625 come from?
GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 711212Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot1Amazon2Apple1China (ByteDance, Huawei, Baidu…)0Others2Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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Aspartate aminotransferase to alanine aminotransferase ratio (rs75920625). MyGeneLog™. https://www.mygenelog.com/variants/rs75920625