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Atrial fibrillation

MYOSLID-AS1 · rs7590537

Where this position leads

Condition: Atrial Fibrillation

rs7590537 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs7590537 rs7590537 MYOSLID-AS1

What the study found

Who was studied 228,926 European ancestry cases, 1,611,415 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0274 higher (95% confidence interval 0.02-0.035); p = 2 × 10−13.

How common The T allele had a frequency of about 67% in the people studied.

Where it sits Chromosome 2, band 2q33.3 — in an intron of MYOSLID-AS1.

What each result means

C/C No copy of the version the research linked to Atrial fibrillation. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Atrial fibrillation. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Atrial fibrillation. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7590537

What is rs7590537?

rs7590537 is a single position in the genome, in or near the MYOSLID-AS1 gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7590537 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs7590537 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7590537 come from?

GWAS Catalog, Nature communications 2025, PMID:40645996. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Atrial fibrillation (rs7590537). MyGeneLog™. https://www.mygenelog.com/variants/rs7590537

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