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Immature reticulocyte fraction (UKB data field 30280)

NCOA4 · rs75901817

Where this position leads

Condition: Celiac Disease

rs75901817 Condition: Celiac Disease Celiac Disease Condition rs75901817 rs75901817 NCOA4

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0587 higher (95% confidence interval 0.047-0.07); p = 5 × 10−27.

How common The G allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 10, band 10q11.22 — in an intron of NCOA4.

What each result means

C/C No copy of the version the research linked to Immature reticulocyte fraction (UKB data field 30280). This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Immature reticulocyte fraction (UKB data field 30280). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Immature reticulocyte fraction (UKB data field 30280). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs75901817

What is rs75901817?

rs75901817 is a single position in the genome, in or near the NCOA4 gene. Published research associates it with immature reticulocyte fraction (ukb data field 30280). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs75901817 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs75901817 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75901817 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Immature reticulocyte fraction (UKB data field 30280) (rs75901817). MyGeneLog™. https://www.mygenelog.com/variants/rs75901817

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