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Neonatal cytokine/chemokine levels (fetal genetic effect)

PLCL2 · rs75885714

What the study found

Who was studied 764 Hispanic, European, Asian, South Asian or African American individuals.

The effect Each copy of the C allele shifted the measure 0.53 lower (95% confidence interval 0.43-0.63); p = 9 × 10−21.

How common The C allele had a frequency of about 8% in the people studied.

Where it sits Chromosome 3, band 3p24.3 — in an intron of PLCL2.

What each result means

A/A No copy of the version the research linked to Neonatal cytokine/chemokine levels (fetal genetic effect). This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Neonatal cytokine/chemokine levels (fetal genetic effect). That is a smaller link than two copies.
C/C Two copies of the version the research linked to Neonatal cytokine/chemokine levels (fetal genetic effect). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs75885714

What is rs75885714?

rs75885714 is a single position in the genome, in or near the PLCL2 gene. Published research associates it with neonatal cytokine/chemokine levels (fetal genetic effect). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs75885714 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75885714 come from?

GWAS Catalog, Genome Med 2018, PMID:30134952. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Neonatal cytokine/chemokine levels (fetal genetic effect) (rs75885714). MyGeneLog™. https://www.mygenelog.com/variants/rs75885714

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