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Who was studied 1,030,836 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.01 lower (95% confidence interval 0.0061-0.0139); p = 1 × 10−8.
Where it sits Chromosome 3, band 3q26.33 — in an intron of GNB4.
What each result means
C/CNo copy of the version the research linked to Atrial fibrillation (MTAG). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Atrial fibrillation (MTAG). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Atrial fibrillation (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Frontiers in cardiovascular medicine · 2022 · PMID 35872910 · open access
Questions about rs75880040
What is rs75880040?
rs75880040 is a single position in the genome, in or near the GNB4 gene. Published research associates it with atrial fibrillation (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs75880040 linked to?
On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.
Does having rs75880040 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs75880040 come from?
GWAS Catalog, Frontiers in cardiovascular medicine 2022, PMID:35872910. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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