Who was studied 2077 British ancestry individuals from 6863 families..
The effect
The reported allele is A; the catalogue records no effect size
; p = 2 × 10−8.
How common The A allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 5, band 5p15.1 — in an intron of RETREG1-AS1.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Urate levels compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Urate levels.
G/GPublished research associates this genotype with typical/baseline likelihood of Urate levels — no copies of the reported risk allele.
Genome medicine · 2017 · PMID 28270201 · open access
Questions about rs75869162
What is rs75869162?
rs75869162 is a single position in the genome, in or near the FAM134B gene. Published research associates it with urate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs75869162 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs75869162 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs75869162 come from?
GWAS Catalog, Genome Med 2017, PMID:28270201. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.