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Educational attainment (years of education)

near RNA5SP107 · rs7584691

Where this position leads

Condition: Educational Attainment

rs7584691 Condition: Educational Attainment Educational Attainment Condition rs7584691 rs7584691 near RNA5SP1…

What the study found

Who was studied up to 1,131,881 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0111 higher (95% confidence interval 0.0084-0.0138); p = 3 × 10−15.

How common The A allele had a frequency of about 53% in the people studied.

Where it sits Chromosome 2, band 2q24.1 — between genes, 33.2 kb from RNA5SP107.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Educational attainment (years of education) compared to the general population.
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Educational attainment (years of education).
C/C Published research associates this genotype with typical/baseline likelihood of Educational attainment (years of education) — no copies of the reported risk allele.
Source
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Lee JJ, Wedow R, Okbay A, Kong E, Maghzian O, Zacher M, Nguyen-Viet TA, Bowers P, Sidorenko J, Karlsson Linnér R, Fontana MA, Kundu T
and 65 more — show all
Lee C, Li H, Li R, Royer R, Timshel PN, Walters RK, Willoughby EA, Yengo L, Alver M, Bao Y, Clark DW, Day FR, Furlotte NA, Joshi PK, Kemper KE, Kleinman A, Langenberg C, Mägi R, Trampush JW, Verma SS, Wu Y, Lam M, Zhao JH, Zheng Z, Boardman JD, Campbell H, Freese J, Harris KM, Hayward C, Herd P, Kumari M, Lencz T, Luan J, Malhotra AK, Metspalu A, Milani L, Ong KK, Perry JRB, Porteous DJ, Ritchie MD, Smart MC, Smith BH, Tung JY, Wareham NJ, Wilson JF, Beauchamp JP, Conley DC, Esko T, Lehrer SF, Magnusson PKE, Oskarsson S, Pers TH, Robinson MR, Thom K, Watson C, Chabris CF, Meyer MN, Laibson DI, Yang J, Johannesson M, Koellinger PD, Turley P, Visscher PM, Benjamin DJ, Cesarini D
23andMe Research Team · COGENT (Cognitive Genomics Consortium) · Social Science Genetic Association Consortium
Nature genetics · 2018 · PMID 30038396

Questions about rs7584691

What is rs7584691?

rs7584691 is a single position in the genome, in or near the near RNA5SP107 gene. Published research associates it with educational attainment (years of education). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7584691 linked to?

On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.

Does having rs7584691 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7584691 come from?

GWAS Catalog, Nature genetics 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Educational attainment (years of education) (rs7584691). MyGeneLog™. https://www.mygenelog.com/variants/rs7584691

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