C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Metastasis in stage I-III microsatellite instability low/stable colorectal cancer (time to event) compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Metastasis in stage I-III microsatellite instability low/stable colorectal cancer (time to event).
T/TPublished research associates this genotype with typical/baseline likelihood of Metastasis in stage I-III microsatellite instability low/stable colorectal cancer (time to event) — no copies of the reported risk allele.
rs7582977 is a single position in the genome, in or near the near SP9 gene. Published research associates it with metastasis in stage i-iii microsatellite instability low/stable colorectal cancer (time to event). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7582977 linked to?
On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs7582977 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7582977 come from?
GWAS Catalog, BMC Cancer 2019, PMID:30738427. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.