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Alanine levels

near GLS · rs7582941

What the study found

Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.

The effect Each copy of the T allele shifted the measure 0.02 mmol/L higher (95% confidence interval 0.02-0.02); p = 1 × 10−12.

Where it sits Chromosome 2, band 2q32.2 — between genes, 16.6 kb from GLS.

What each result means

A/A No copy of the version the research linked to Alanine levels. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Alanine levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Alanine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7582941

What is rs7582941?

rs7582941 is a single position in the genome, in or near the near GLS gene. Published research associates it with alanine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7582941 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7582941 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Alanine levels (rs7582941). MyGeneLog™. https://www.mygenelog.com/variants/rs7582941

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