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Fasting glucose

SPC25 · rs7582529

What the study found

Who was studied 16,579 African American individuals.

The effect Each copy of the T allele shifted the measure 0.0531 higher; p = 7 × 10−13.

How common The T allele had a frequency of about 19% in the people studied.

Where it sits Chromosome 2, band 2q24.3 — in an intron of SPC25.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of Fasting glucose — no copies of the reported risk allele.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Fasting glucose.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Fasting glucose compared to the general population.
Source

Questions about rs7582529

What is rs7582529?

rs7582529 is a single position in the genome, in or near the SPC25 gene. Published research associates it with fasting glucose. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7582529 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7582529 come from?

GWAS Catalog, Nature genetics 2021, PMID:34059833. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Fasting glucose (rs7582529). MyGeneLog™. https://www.mygenelog.com/variants/rs7582529

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