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Cognitive decline rate in late mild cognitive impairment

MYT1L · rs7581969

Where this position leads

Condition: Cognitive Decline Rate in Late MCI

rs7581969 Condition: Cognitive Decline Rate in Late MCI Cognitive Decline Rate in Late MCI Condition rs7581969 rs7581969 MYT1L

What the study found

Who was studied 472 European ancestry cases, 47 cases.

The effect Each copy of the C allele shifted the measure 0.551 higher (95% confidence interval 0.38-0.72); p = 5 × 10−10.

How common The C allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 2, band 2p25.3 — in an intron of LOC107985840.

What each result means

C/C Two copies of the version the research linked to Cognitive decline rate in late mild cognitive impairment. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Cognitive decline rate in late mild cognitive impairment. That is a smaller link than two copies.
T/T No copy of the version the research linked to Cognitive decline rate in late mild cognitive impairment. This is the starting point the study compared everyone against.
Source

Questions about rs7581969

What is rs7581969?

rs7581969 is a single position in the genome, in or near the MYT1L gene. Published research associates it with cognitive decline rate in late mild cognitive impairment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7581969 linked to?

On MyGeneLog this position is linked to Cognitive Decline Rate in Late MCI. The research behind each link, and its sources, are set out on that condition page.

Does having rs7581969 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7581969 come from?

GWAS Catalog, PLoS One 2015, PMID:26252872. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cognitive decline rate in late mild cognitive impairment (rs7581969). MyGeneLog™. https://www.mygenelog.com/variants/rs7581969

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