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X-21834 levels

near CYP2C9 · rs75794524

What the study found

Who was studied 14,296 European ancestry individuals; replicated in 5,698 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.189 higher (95% confidence interval 0.14-0.23); p = 2 × 10−16.

How common The A allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 10, band 10q23.33 — between genes, 3.8 kb from CYP2C9.

What each result means

A/A Two copies of the version the research linked to X-21834 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to X-21834 levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to X-21834 levels. This is the starting point the study compared everyone against.
Source

Questions about rs75794524

What is rs75794524?

rs75794524 is a single position in the genome, in or near the near CYP2C9 gene. Published research associates it with x-21834 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs75794524 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75794524 come from?

GWAS Catalog, Nature medicine 2022, PMID:36357675. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

X-21834 levels (rs75794524). MyGeneLog™. https://www.mygenelog.com/variants/rs75794524

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