Sensitive

Prostate cancer

PCAT1 · rs75777376

Where this position leads

Condition: Prostate Cancer

rs75777376 Condition: Prostate Cancer Prostate Cancer Condition rs75777376 rs75777376 PCAT1

What the study found

Who was studied 5,088 Japanese ancestry cases, 10,682 Japanese ancestry controls; replicated in 4,818 Japanese ancestry cases, 73,261 Japanese ancestry controls.

The effect The reported allele is C; the catalogue records no effect size ; p = 1 × 10−20.

How common The C allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 8, band 8q24.21 — in an intron of PCAT1.

What each result means

C/C Two copies of the version the research linked to Prostate cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Prostate cancer. That is a smaller link than two copies.
T/T No copy of the version the research linked to Prostate cancer. This is the starting point the study compared everyone against.
Source

Questions about rs75777376

What is rs75777376?

rs75777376 is a single position in the genome, in or near the PCAT1 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs75777376 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs75777376 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75777376 come from?

GWAS Catalog, Nature communications 2019, PMID:31562322. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Prostate cancer (rs75777376). MyGeneLog™. https://www.mygenelog.com/variants/rs75777376

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