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Hip bone size

near RPS20P12 · rs7575512

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 3,267 European ancestry individuals, 1,619 Chinese ancestry individuals, 843 African American individuals, 446 Hispanic individuals.

The effect Each copy of the T allele shifted the measure 0.13 higher (95% confidence interval 0.091-0.169); p = 3 × 10⁻¹⁰.

Where it sits Chromosome 2, band 2q37.1 — between genes, 27.8 kb from RPS20P12.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Hip bone size — no copies of the reported risk allele.

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hip bone size.

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hip bone size compared to the general population.

Source

Pleiotropic loci underlying bone mineral density and bone size identified by a bivariate genome-wide association analysis

Zhang H, Liu L, Ni JJ, Wei XT, Feng GJ, Yang XL, Xu Q, Zhang ZJ, Hai R, Tian Q, Shen H, Deng HW

and 2 more — show all

Pei YF, Zhang L

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020 · PMID 32314116

Questions about rs7575512

What is rs7575512?

rs7575512 is a single position in the genome, in or near the near RPS20P12 gene. Published research associates it with hip bone size. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7575512 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7575512 come from?

GWAS Catalog, Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2020, PMID:32314116. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hip bone size (rs7575512). MyGeneLog™. https://www.mygenelog.com/variants/rs7575512

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