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Mean corpuscular hemoglobin in pregnancy

USP49 · rs75746803

What the study found

Who was studied 90,166 Chinese ancestry individuals; replicated in 43,598 Chinese ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.292 lower (95% confidence interval 0.24-0.34); p = 1 × 10−28.

How common The G allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 6, band 6p21.1 — a missense change in USP49.

What each result means

C/C No copy of the version the research linked to Mean corpuscular hemoglobin in pregnancy. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Mean corpuscular hemoglobin in pregnancy. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Mean corpuscular hemoglobin in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs75746803

What is rs75746803?

rs75746803 is a single position in the genome, in or near the USP49 gene. Published research associates it with mean corpuscular hemoglobin in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs75746803 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75746803 come from?

GWAS Catalog, Nature genetics 2026, PMID:42509370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean corpuscular hemoglobin in pregnancy (rs75746803). MyGeneLog™. https://www.mygenelog.com/variants/rs75746803

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