Standard

HDL cholesterol levels

NUP93 · rs75745425

What the study found

Who was studied 58,701 Korean ancestry individuals.

The effect Each copy of the T allele shifted the measure 2.51 higher (95% confidence interval 1.88-3.14); p = 6 × 10−15.

Where it sits Chromosome 16, band 16q13 — in an intron of NUP93.

What each result means

A/A No copy of the version the research linked to HDL cholesterol levels. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to HDL cholesterol levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to HDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs75745425

What is rs75745425?

rs75745425 is a single position in the genome, in or near the NUP93 gene. Published research associates it with hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs75745425 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75745425 come from?

GWAS Catalog, Biomedicines 2022, PMID:35884923. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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HDL cholesterol levels (rs75745425). MyGeneLog™. https://www.mygenelog.com/variants/rs75745425

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