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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 85,750 European ancestry middle-aged adult individuals.
The effect
Each copy of the G allele shifted the measure 0.139 lower (95% confidence interval 0.1-0.18); p = 1 × 10−12.
How common The G allele had a frequency of about 7% in the people studied.
Where it sits Chromosome 4, band 4q13.3 — between genes, 48.3 kb from ADAMTS3.
What each result means
A/ANo copy of the version the research linked to Appendicular lean mass. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Appendicular lean mass. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Appendicular lean mass. That is the strongest link of the three results. A link in a study is not a diagnosis.
American journal of human genetics · 2019 · PMID 31761296
Questions about rs75682840
What is rs75682840?
rs75682840 is a single position in the genome, in or near the near ADAMTS3 gene. Published research associates it with appendicular lean mass. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs75682840 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs75682840 come from?
GWAS Catalog, American journal of human genetics 2019, PMID:31761296. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Appendicular lean mass (rs75682840). MyGeneLog™. https://www.mygenelog.com/variants/rs75682840