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Gamma glutamyl transferase levels

MLXIP · rs75661051

What the study found

Who was studied 875,069 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0043 higher (95% confidence interval 0.0031-0.0055); p = 1 × 10−11.

Where it sits Chromosome 12, band 12q24.31 — in an intron of MLXIP.

What each result means

A/A No copy of the version the research linked to Gamma glutamyl transferase levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Gamma glutamyl transferase levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Gamma glutamyl transferase levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs75661051

What is rs75661051?

rs75661051 is a single position in the genome, in or near the MLXIP gene. Published research associates it with gamma glutamyl transferase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs75661051 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75661051 come from?

GWAS Catalog, Nature genetics 2024, PMID:38632349. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Gamma glutamyl transferase levels (rs75661051). MyGeneLog™. https://www.mygenelog.com/variants/rs75661051

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