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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,185 European ancestry adolescent individuals; replicated in 1,622 European ancestry adolescent individuals.
The effect
Each copy of the G allele shifted the measure 0.388 mm higher (95% confidence interval 0.30-0.48); p = 4 × 10−16.
Where it sits Chromosome 2, band 2q36.1 — in an intron of PAX3.
What each result means
A/ANo copy of the version the research linked to Facial morphology. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Facial morphology. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Facial morphology. That is the strongest link of the three results. A link in a study is not a diagnosis.
American journal of human genetics · 2012 · PMID 22341974
Questions about rs7559271
What is rs7559271?
rs7559271 is a single position in the genome, in or near the PAX3 gene. Published research associates it with facial morphology. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7559271 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7559271 come from?
GWAS Catalog, Am J Hum Genet 2012, PMID:22341974. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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