Allergic disease (asthma, hay fever and/or eczema) (age of onset)
FOSL2 · rs7559046
0 16122110Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 117,130 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.031 lower (95% confidence interval 0.023-0.039); p = 3 × 10−13.
How common The C allele had a frequency of about 54% in the people studied.
Where it sits Chromosome 2, band 2p23.2 — between genes, 4.5 kb from FOSL2.
What each result means
C/CTwo copies of the version the research linked to Allergic disease (asthma, hay fever and/or eczema) (age of onset). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Allergic disease (asthma, hay fever and/or eczema) (age of onset). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Allergic disease (asthma, hay fever and/or eczema) (age of onset). This is the starting point the study compared everyone against.
PLoS genetics · 2020 · PMID 32603359 · open access
Questions about rs7559046
What is rs7559046?
rs7559046 is a single position in the genome, in or near the FOSL2 gene. Published research associates it with allergic disease (asthma, hay fever and/or eczema) (age of onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7559046 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs7559046 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7559046 come from?
GWAS Catalog, PLoS genetics 2020, PMID:32603359. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 16122110Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Allergic disease (asthma, hay fever and/or eczema) (age of onset) (rs7559046). MyGeneLog™. https://www.mygenelog.com/variants/rs7559046