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Glycated hemoglobin levels

CARMIL1 · rs75580845

What the study found

Who was studied 146,806 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0203 higher (95% confidence interval 0.016-0.025); p = 1 × 10−20.

How common The T allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 6, band 6p22.2 — in an intron of CARMIL1.

What each result means

C/C No copy of the version the research linked to Glycated hemoglobin levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Glycated hemoglobin levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Glycated hemoglobin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs75580845

What is rs75580845?

rs75580845 is a single position in the genome, in or near the CARMIL1 gene. Published research associates it with glycated hemoglobin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs75580845 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75580845 come from?

GWAS Catalog, Nature genetics 2021, PMID:34059833. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Glycated hemoglobin levels (rs75580845). MyGeneLog™. https://www.mygenelog.com/variants/rs75580845

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