Standard

Physical function (baseline)

KIF18B · rs755547

What the study found

Who was studied 405,979 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0139 lower (95% confidence interval 0.011-0.017); p = 7 × 10−25.

How common The G allele had a frequency of about 81% in the people studied.

Where it sits Chromosome 17, band 17q21.31 — a synonymous change in KIF18B.

What each result means

A/A No copy of the version the research linked to Physical function (baseline). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Physical function (baseline). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Physical function (baseline). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs755547

What is rs755547?

rs755547 is a single position in the genome, in or near the KIF18B gene. Published research associates it with physical function (baseline). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs755547 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs755547 come from?

GWAS Catalog, Nature communications 2025, PMID:40374629. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Physical function (baseline) (rs755547). MyGeneLog™. https://www.mygenelog.com/variants/rs755547

← See all variants