1 231122215Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others15Total23Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0234 lower (95% confidence interval 0.02-0.027); p = 2 × 10−33.
Where it sits Chromosome 1, band 1p31.1 — in an intron of TNNI3K.
What each result means
A/ATwo copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Body mass index. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Nature communications · 2025 · PMID 40436827 · open access
Questions about rs7553158
What is rs7553158?
rs7553158 is a single position in the genome, in or near the TNNI3K gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7553158 linked to?
On MyGeneLog this position is linked to Obesity and Body Weight, Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.
Does having rs7553158 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7553158 come from?
GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 231122215Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others15Total23Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Body mass index (rs7553158). MyGeneLog™. https://www.mygenelog.com/variants/rs7553158