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C-reactive protein

CRP · rs7553007

Where this position leads

Condition: C-Reactive Protein Levels

rs7553007 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs7553007 rs7553007 CRP

What the study found

Who was studied 17,967 European ancestry and Indian Asian ancestry individuals; replicated in 13,615 European ancestry and Indian Asian ancestry Individuals.

The effect Each copy of the A allele shifted the measure 20.7 % lower (95% confidence interval 18.9-23.4); p = 8 × 10−44.

Where it sits Chromosome 1, band 1q23.2 — between genes, 14.2 kb from CRP.

What each result means

A/A Two copies of the version the research linked to C-reactive protein. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to C-reactive protein. That is a smaller link than two copies.
G/G No copy of the version the research linked to C-reactive protein. This is the starting point the study compared everyone against.
Source

Questions about rs7553007

What is rs7553007?

rs7553007 is a single position in the genome, in or near the CRP gene. Published research associates it with c-reactive protein. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7553007 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs7553007 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7553007 come from?

GWAS Catalog, JAMA 2009, PMID:19567438. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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C-reactive protein (rs7553007). MyGeneLog™. https://www.mygenelog.com/variants/rs7553007

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