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Spontaneous dizygotic twinning

ARL14EP-DT · rs75525300

What the study found

Who was studied 3,273 European ancestry female cases, 24,009 European ancestry female controls.

The effect Each copy of the G allele shifted the measure 0.352 lower (95% confidence interval 0.27-0.44); p = 2 × 10−16.

How common The G allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 11, band 11p14.1 — in an intron of ARL14EP-DT.

What each result means

A/A No copy of the version the research linked to Spontaneous dizygotic twinning. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Spontaneous dizygotic twinning. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Spontaneous dizygotic twinning. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs75525300

What is rs75525300?

rs75525300 is a single position in the genome, in or near the ARL14EP-DT gene. Published research associates it with spontaneous dizygotic twinning. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs75525300 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75525300 come from?

GWAS Catalog, Twin research and human genetics : the official journal of the International Society for Twin Studies 2023, PMID:37994447. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Spontaneous dizygotic twinning (rs75525300). MyGeneLog™. https://www.mygenelog.com/variants/rs75525300

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