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Male-pattern baldness

near TRHR · rs75520281

Where this position leads

Condition: Androgenetic Alopecia (Male Pattern Baldness)

rs75520281 Condition: Androgenetic Alopecia (Male Pattern Baldness) Androgenetic Alopecia (Male Pattern… Condition rs75520281 rs75520281 near TRHR

What the study found

Who was studied 52,874 British ancestry males.

The effect Each copy of the G allele shifted the measure 0.221 higher; p = 2 × 10−14.

Where it sits Chromosome 8, band 8q23.1 — between genes, 123.9 kb from TRHR.

What each result means

A/A No copy of the version the research linked to Male-pattern baldness. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Male-pattern baldness. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Male-pattern baldness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs75520281

What is rs75520281?

rs75520281 is a single position in the genome, in or near the near TRHR gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs75520281 linked to?

On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.

Does having rs75520281 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75520281 come from?

GWAS Catalog, PLoS Genet 2017, PMID:28196072. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Male-pattern baldness (rs75520281). MyGeneLog™. https://www.mygenelog.com/variants/rs75520281

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