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Systolic blood pressure (MTAG)

LFNG · rs755179

Where this position leads

Condition: Blood Pressure

rs755179 Condition: Blood Pressure Blood Pressure Condition rs755179 rs755179 LFNG

What the study found

Who was studied at least 757,601 European ancestry individuals (MTAG boosted by 455,258 Alzheimer's disease samples).

The effect Each copy of the T allele shifted the measure 0.0102 higher (95% confidence interval 0.0067-0.0136); p = 5 × 10−9.

Where it sits Chromosome 7, band 7p22.3 — in a regulatory region of LFNG.

What each result means

C/C No copy of the version the research linked to Systolic blood pressure (MTAG). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Systolic blood pressure (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Systolic blood pressure (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs755179

What is rs755179?

rs755179 is a single position in the genome, in or near the LFNG gene. Published research associates it with systolic blood pressure (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs755179 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs755179 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs755179 come from?

GWAS Catalog, Nature communications 2024, PMID:39537608. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Systolic blood pressure (MTAG) (rs755179). MyGeneLog™. https://www.mygenelog.com/variants/rs755179

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