Standard

Physical activity (walking duration)

HP1BP3 · rs7548269

What the study found

Who was studied 91,105 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.027 SD units lower (95% confidence interval 0.017-0.037); p = 2 × 10−8.

How common The T allele had a frequency of about 61% in the people studied.

Where it sits Chromosome 1, band 1p36.12 — in an intron of HP1BP3.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Physical activity (walking duration) — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Physical activity (walking duration).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Physical activity (walking duration) compared to the general population.
Source

Questions about rs7548269

What is rs7548269?

rs7548269 is a single position in the genome, in or near the HP1BP3 gene. Published research associates it with physical activity (walking duration). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7548269 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7548269 come from?

GWAS Catalog, Nat Commun 2018, PMID:30531941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Physical activity (walking duration) (rs7548269). MyGeneLog™. https://www.mygenelog.com/variants/rs7548269

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