Ventricular ectopy or supraventricular ectopy (pleiotropy)
CDKN2C · rs7545860
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,618 European ancestry supraventricular ectopy cases, 652 African ancestry supraventricular ectopy cases, 354 Hispanic/Latino ancestry supraventricular ectopy cases, 2,468 European ancestry ventricular ectopy cases, 481 African ancestry ventricular ectopy cases, 168 Hispanic/Latino ancestry ventricular ectopy cases, at least 19,586 European ancestry controls, at least 8,141 African ancestry controls, at least 10,663 Hispanic/Latino ancestry controls..
The effect
The reported allele is A; the catalogue records no effect size
; p = 1 × 10−8.
How common The A allele had a frequency of about 98% in the people studied.
Where it sits Chromosome 1, band 1p32.3 — in an intron of FAF1.
What each result means
A/ATwo copies of the version the research linked to Ventricular ectopy or supraventricular ectopy (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Ventricular ectopy or supraventricular ectopy (pleiotropy). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Ventricular ectopy or supraventricular ectopy (pleiotropy). This is the starting point the study compared everyone against.
Scientific reports · 2018 · PMID 29618737 · open access
Questions about rs7545860
What is rs7545860?
rs7545860 is a single position in the genome, in or near the CDKN2C gene. Published research associates it with ventricular ectopy or supraventricular ectopy (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7545860 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7545860 come from?
GWAS Catalog, Sci Rep 2018, PMID:29618737. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Ventricular ectopy or supraventricular ectopy (pleiotropy) (rs7545860). MyGeneLog™. https://www.mygenelog.com/variants/rs7545860