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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,466 Black/admixed ancestry individuals; replicated in up to 1,653 European, Hispanic, Asian or Black individuals.
The effect
Each copy of the A allele shifted the measure 1.54 higher (95% confidence interval 1.31-1.77); p = 3 × 10−39.
Where it sits Chromosome 3, band 3p21.2 — in an intron of PCBP4.
What each result means
A/ATwo copies of the version the research linked to N-acetylalanine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to N-acetylalanine levels. That is a smaller link than two copies.
C/CNo copy of the version the research linked to N-acetylalanine levels. This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 35995766 · open access
Questions about rs754490766
What is rs754490766?
rs754490766 is a single position in the genome, in or near the PCBP4 gene. Published research associates it with n-acetylalanine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs754490766 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs754490766 come from?
GWAS Catalog, Nature communications 2022, PMID:35995766. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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