Sensitive

Alcohol use disorder

near FAM177A1P1 · rs75438204

Where this position leads

Condition: Alcohol Use Disorder

rs75438204 Condition: Alcohol Use Disorder Alcohol Use Disorder Condition rs75438204 rs75438204 near FAM177A…

What the study found

Who was studied 296,989 European ancestry individuals, 80,764 African American individuals, 31,877 Hispanic American individuals.

The effect Each copy of the T allele shifted the measure 5.63 z-score lower; p = 2 × 10−8.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 4, band 4q23 — between genes, 0.4 kb from FAM177A1P1.

What each result means

C/C No copy of the version the research linked to Alcohol use disorder. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Alcohol use disorder. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Alcohol use disorder. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs75438204

What is rs75438204?

rs75438204 is a single position in the genome, in or near the near FAM177A1P1 gene. Published research associates it with alcohol use disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs75438204 linked to?

On MyGeneLog this position is linked to Alcohol Use Disorder. The research behind each link, and its sources, are set out on that condition page.

Does having rs75438204 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75438204 come from?

GWAS Catalog, The American journal of psychiatry 2023, PMID:37282553. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Alcohol use disorder (rs75438204). MyGeneLog™. https://www.mygenelog.com/variants/rs75438204

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